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KMID : 0351819920330030239
Kyunpook University Medical Journal
1992 Volume.33 No. 3 p.239 ~ p.250
Status of Esterogene and Progesterone Receptor of Breast Cancer Tissues in Korean
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Abstract
The levels of estrogen receptors (ER) ad Progesterone receptors (PR) in 39 breast cancer tissues have been determined and a correlation of both receptor levels with the histopathologic findings and clinical features was attempted.
The
ER
levels ranged from 0 to 230.02 fmol/mg cytosol protein and the PR levels ranged from 0 to 66.60 fmol/mg cytosol protein 33% of the specimens were ER+and 56% were PR+. The group younger than 50 years had a higher percentage of positive PR
status.
The positive rate of ER showed no significant difference between pre-and postmenopause, while those of PR was decreased from 67% in preto 41% in postmenopause. 82% of the histologic type were infiltrating ductal carcinoma and 74% of patients
were
stage II of TNM classification.
These results indicated that there was strong correlation between age, menopausal status, axillary lymph node metastasis, TNM stage and receptor status.
KEYWORD
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